媳妇的美好时代

Are 3D mammograms better than standard imaging? A diverse study aims to find out_我的网站

一 |     AI摘要      台媒人分析陈幸妤婚变风波，指其爆料节奏缜密、异于往常，疑似精心布局的复仇策略。    Are 3D mammograms better than standard 2D imaging for catching advanced cancers?A clinical trial is recruiting thousands of volunteers — including a large number of Black women who face disparities in breast cancer death rates — to try to find out.People like Carole Stovall, a psychologist in Washington, D.C., have signed up for the study to help answer the question.“We all need a mammogram anyway, so why not do it with a study that allows the scientists to understand more and move closer to finding better treatments and ways of maybe even preventing it?” Stovall said.The underrepresentation of women and minorities in research is a long-simmering issue affecting health problems including Alzheimer’s disease, stroke and COVID-19. Trials without diversity lead to gaps in understanding of how new treatments work for all people. “Until we get more Black women into clinical trials, we can’t change the science. And we need better science for Black bodies,” said Ricki Fairley, a breast cancer survivor and advocate who is working on the issue.Black women are 40% more likely to die from breast cancer than white women and tend to be diagnosed younger. But it’s not clear whether 3D mammography is better for them, said Dr. Worta McCaskill-Stevens of the National Cancer Institute.“Are there populations for whom this might be important to have early diagnosis?" asked McCaskill-Stevens. "Or is it harmful,” causing too many false alarms or unneeded follow-up tests and treatments?McCaskill-Stevens, who is Black, leads NCI’s efforts to boost access to cancer research in minority and rural communities. She has joined the study herself.The newer 3D technique has been around for a decade, but there’s never been conclusive evidence that it's better than 2D at detecting advanced cancers. The screening technique combines multiple pictures of the breast taken from different angles to create a 3D-like image. Both 3D and 2D mammograms compress the breast and use low doses of radiation.Prior studies suggest that 3D finds more cancers than 2D, but catching more cancers doesn’t necessarily mean more lives saved. Some cancers missed by standard screening may not progress or need treatment. Previous studies did not randomly assign patients to a screening method, the gold standard for research.The notion “that if it’s new, it’s shiny, then it’s better,” isn’t necessarily true, McCaskill-Stevens said. “Until we have the evidence to support that, then we need well-designed randomized trials.”The trial has enrolled nearly 93,000 women so far with a goal of 128,000. The NCI-funded study is now running in Canada, South Korea, Peru, Argentina, Italy and 32 U.S. states. A site in Thailand will soon begin enrolling patients.“We added more international sites to enhance the trial’s diversity, particularly for Hispanic and Asian women,” said Dr. Etta Pisano, who leads the study. Overall, 42% of participants are Hispanic. As recruiting continues, enrolling Black women and other women of color will “absolutely” continue as a priority, Pisano said.Participants are randomly assigned to either 2D or 3D mammograms and are followed for several years. The number of advanced cancers detected by the two methods will be compared.At the U.S. study sites, 21% of study participants are Black women — that's higher than a typical cancer treatment study, in which 9% of participants are Black, McCaskill-Stevens said.The University of North Carolina has signed up more Black women than any other study site. Nearly a quarter of the nearly 3,000 women enrolled at UNC’s two locations are Black.“Women in North Carolina want to take part in something that’s bigger than them,” said Dr. Cherie Kuzmiak, who leads the UNC arm of the study. “They want this active role in helping determine the future of health care for women.”In Washington, D.C., word of mouth has led to successful recruiting. A chance encounter at her hair salon persuaded Stovall to join the research. While waiting for a hair appointment, she met Georgetown University cancer researcher Lucile Adams-Campbell. The two, both Black, started chatting.“She explained how important it was to get women of color into the program,” said Stovall, who jumped at the chance to catch up on her mammograms after the COVID-19 pandemic delayed screening for her and thousands of others.For Stovall, there was a personal reason to join the research. Her sister recently completed treatment for triple negative breast cancer, an aggressive type that affects Black women at higher rates than white women. Women ages 45 to 74 without a personal history of breast cancer are eligible for the study, which launched in 2017. Many women also are providing blood and cheek swab samples for a database that will be mined for insights.“It’s a dream that people had since the beginning of screening that we wouldn’t fit everybody into the same box,” Pisano said. The study's findings could “reduce disparities if we’re successful, assuming people have access to care.”Stovall, 72, had a brief scare when her mammogram, the traditional 2D type, showed something suspicious. A biopsy ruled out cancer.“I was extremely relieved,” Stovall said. “Everybody I know has heard from me about the need for them to go get a mammogram.”___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.。此举旨在借舆论施压赵建铭，核心牵涉离婚条件及财产分配争议。

二 |          台湾地区前领导人陈水扁之女陈幸妤近期主动揭开婚变风波，不仅以“前妻”身份在赵建铭诊所留下评价，更接连曝出婚姻纠纷、控诉前夫，话题持续延烧。陈水扁随后公开向女儿致歉，让整件事热度再攀新高。台湾媒体人谢寒冰分析，陈幸妤此次爆料节奏缜密、层层递进，绝非随性情绪爆发，疑似有高人幕后布局，是一套精心安排的策略，预判赵建铭未来将承受巨大舆论压力。         谢寒冰17日直言，整件事的发展轨迹并不简单。他分析，陈幸妤过往性格直率、喜怒直白，遇事向来直来直往，几乎不会刻意铺陈节奏、分步爆料。但此次婚变风波，全程条理清晰、循序渐进，完全不同于她以往的行事风格。

三 |     谢寒冰拆解完整脉络：事件初期，陈幸妤先在赵建铭经营的骨科诊所社交媒体评论区留下争议留言，内容迅速被网友截图、扩散至各大社群。在外界纷纷揣测真假之际，她立刻亲自证实、承认留言属实，坐实婚变传闻。    舆论发酵后，陈幸妤再顺势陆续抛出金钱纠葛、家庭矛盾等内幕，紧接着陈水扁发文致歉、心疼女儿，一连串动作环环相扣、步步推进。对此，谢寒冰直言认为，整起风波就是精心设计的剧本，堪称前妻的复仇布局。

四 |     针对背后动机，谢寒冰推测，除了借舆论施压赵建铭，核心更牵涉双方离婚条件、财产分配与金钱争议，是有目标、有节奏的维权反击。    最后他坦言，随着风波持续延烧，赵建铭的一举一动都将被舆论放大检视，言行、行程与人脉往来都会成为话题焦点，后续争议只会越来越多。谢寒冰表示，接下来赵建铭的日子，将会非常不好过，双方后续攻防值得持续关注。

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